Reliable Vial Sealing Starts with a Stopper That Fits the Entire Closure System
A pharmaceutical stopper must do more than fit inside a vial. Dimensional variation, unsuitable elastomer selection, inconsistent flange thickness, or mismatched crimp components can cause difficult stoppering, unstable compression, crimping problems, and lengthy packaging qualification.
Supply-Packagings supplies red pharmaceutical butyl rubber stoppers for compatible injection vials, penicillin bottles, diagnostic products, veterinary packaging, and laboratory applications.
The product shown features a circular flange, raised central access area, and hollow plug structure designed to seat inside a compatible vial neck. Exact material, dimensions, treatment, and application are specified according to each project.
Key Product Benefits
🔴 Bromobutyl and chlorobutyl elastomer options for pharmaceutical packaging programs
🔴 Molded plug geometry supports stable positioning in compatible vial necks
🔴 Broad flange provides a controlled compression interface under an aluminum closure
🔴 Defined central access zone supports appropriate pharmaceutical handling after sealing
🔴 Multiple sizes available for common vial and penicillin bottle systems
🔴 Coated or siliconized configurations can be evaluated according to process requirements
🔴 Matching glass vials and aluminum flip-off caps reduce cross-supplier tolerance problems
🔴 OEM and ODM support for dimensions, formulation requirements, treatments, and packing
🔴 Factory-direct manufacturer and wholesale supplier for global custom packaging procurement
Product Overview
This is a pharmaceutical elastomeric vial stopper designed to be inserted into the neck of a compatible pharmaceutical glass container and mechanically retained using an aluminum crimp seal or aluminum-plastic flip-off cap.
The image shows three views of the same general stopper style:
- Underside view showing the hollow central plug
- Angled view showing the flange and central molded feature
- Top view showing the circular access region
Common international purchasing names include:
- Red butyl rubber stopper
- Injection vial stopper
- Pharmaceutical rubber stopper
- Penicillin bottle stopper
- Serum vial stopper
- Crimp vial rubber closure
- Pharmaceutical elastomeric closure
How the Vial Stopper System Works
The Stopper Enters the Vial Neck
The lower plug portion is dimensioned to engage a compatible vial neck. Correct interference and elastomer properties help achieve consistent seating.
The Flange Contacts the Vial Lip
The upper flange rests against the vial mouth and provides an important sealing interface.
An Aluminum Closure Retains the Stopper
After stoppering, an aluminum crimp seal or flip-off cap is applied over the flange and formed beneath the vial neck finish.
The Complete System Protects the Product
Final performance is determined by the combined vial, stopper, aluminum closure, product, processing conditions, and validated filling workflow.
Common Stopper Sourcing Problems
Stopper Is Too Tight During Insertion
Excessive interference between stopper plug and vial bore can increase insertion force, cause seating problems, or affect filling-line speed.
We recommend evaluating actual production vials and stopper samples together.
Stopper Feels Too Loose
Insufficient engagement can complicate handling before crimping and may indicate dimensional incompatibility.
Stopper Pops Up Before Crimping
Elastomer recovery, stopper dimensions, vial geometry, insertion depth, and processing conditions can all contribute to pop-up behavior.
Crimp Cap Does Not Seat Correctly
Flange height and stopper compression influence the final stack height beneath the aluminum closure. Matching all three components helps reduce variation.
Material Compatibility Is Uncertain
Elastomer selection should not be based on color or appearance alone. Compatibility with the formulation and processing conditions must be qualified for the intended pharmaceutical use.
Structural Features
Circular Sealing Flange
The wide flange provides a defined surface for compression against the vial lip after crimping.
Hollow Plug
The underside plug engages the vial neck while reducing unnecessary material in the center of the stopper structure.
Central Access Region
The molded center identifies the primary access area in compatible pharmaceutical vial systems.
Rounded Transition Geometry
Smooth transitions between flange and plug help support molding consistency and appropriate seating inside the vial.
Material Options
Bromobutyl Rubber
Bromobutyl elastomers are widely used for pharmaceutical closures because of their low permeability and useful resistance characteristics.
Chlorobutyl Rubber
Chlorobutyl is another widely specified pharmaceutical closure material and can be evaluated according to formulation and process requirements.
Surface-Treated Stoppers
Depending on the project, available configurations may include:
- Siliconized surfaces
- Polymer-coated surfaces
- Reduced-friction treatments
- Application-specific barrier treatments
The final choice should be determined through compatibility, extractables and leachables, processing, stability, and regulatory evaluation.
Technical Specifications
| Parameter | Available Options |
|---|---|
| Product Type | Pharmaceutical butyl rubber vial stopper |
| Material | Bromobutyl / chlorobutyl |
| Standard Appearance | Red or project-specific elastomer color |
| Structure | Flanged hollow-plug stopper |
| Common Sizes | 13mm / 20mm and other compatible specifications |
| Surface | Standard, siliconized or coated by project |
| Compatible Container | Pharmaceutical glass vial / penicillin bottle |
| Compatible Closure | Aluminum crimp seal / flip-off cap |
| Application | Liquid, powder, diagnostic, veterinary and compatible products |
| OEM | Existing specifications with project-specific requirements |
| ODM | Custom dimensions subject to technical feasibility |
| MOQ | Depends on material, size, treatment and packing |
| Samples | Available for selected specifications |
| Packing | Sealed clean inner bags and reinforced cartons |
| Shipping | Sea, air, express |
| Trade Terms | FOB, CIF, DDP according to destination |
Final stopper dimensions, elastomer formulation, cleanliness, sterilization status, surface treatment, technical documentation, and regulatory specifications are confirmed for each individual program.
Compatible Vial Closure Components
Clear Pharmaceutical Glass Vials
Suitable where product visibility and visual inspection are priorities.
Amber Pharmaceutical Vials
Useful when the product stability strategy requires additional light shielding.
Aluminum Crimp Seals
Standard aluminum caps mechanically retain the stopper after appropriate application.
Aluminum-Plastic Flip-Off Caps
Colored flip-off closures combine mechanical retention with convenient access and visual SKU coding.
Secondary Packaging
Protective trays, paper cartons, and dividers can be customized for individual vials and multi-vial kits.
Industries Served
♦ Pharmaceutical Containers — compatible injection, liquid, powder, and penicillin vial systems
♦ Biotechnology — research reagents, biological preparations, and professional laboratory products
♦ Diagnostics — reagents, controls, calibrators, and sample packaging
♦ Veterinary Pharmaceuticals — compatible veterinary vial closure systems
♦ Contract Manufacturing — filling, stoppering, capping, and secondary packaging facilities
♦ Professional Cosmetic Packaging — selected clinic-style vial products where pharmaceutical closure systems are appropriate
Application Scenarios
🩸 Liquid pharmaceutical vial closure systems
💊 Powder and reconstitution vial packaging
🧪 Diagnostic reagent packaging
🐾 Veterinary pharmaceutical vial systems
🏥 Clinical and hospital multi-vial kits
📦 Export programs using matched vial, stopper, flip-off cap, and carton packaging
Product Advantages
Matched Components Reduce Qualification Friction
A stopper cannot be correctly evaluated without the vial and cap. Supply-Packagings can coordinate these components so buyers have fewer tolerance interfaces to troubleshoot.
Multiple Pharmaceutical Elastomer Options
Bromobutyl, chlorobutyl, treated, and coated configurations allow technical teams to evaluate options against formulation and process requirements.
OEM and ODM Support
Existing stopper structures can be customized for project requirements, while special dimensions can be evaluated for sufficiently large ODM programs.
Stable Wholesale Procurement
Approved dimensions, treatment requirements, packing specifications, and lot identification can be maintained for repeat purchasing programs.
Broader Custom Packaging Supply
Supply-Packagings supports pharmaceutical closures alongside bottle, jar, pouch, supplement packaging, aluminum caps, labels, trays, and paper cartons for consolidated global procurement.
Quality Control
Depending on project specification, checkpoints can include:
● Flange diameter and thickness
● Plug outside and inside dimensions
● Stopper overall height
● Visual molding inspection
● Surface treatment confirmation
● Fit evaluation with approved vial references
● Stopper and cap stack-height evaluation
● Packing cleanliness inspection
● Batch identification and traceability
For pharmaceutical use, final qualification remains the responsibility of the drug-product manufacturer and may include chemical compatibility, extractables and leachables, penetration, fragmentation, reseal testing where relevant, container closure integrity, sterilization validation, particulate evaluation, and stability studies.
Packaging and Logistics
Controlled Inner Packing
Stoppers can be supplied in sealed clean inner bags with batch identification and protective outer cartons. Packaging format is selected according to the customer’s subsequent washing, sterilization, filling, and handling process.
Sterility status must be explicitly defined in the agreed purchasing specification and should never be inferred from product appearance or packaging alone.
Global Delivery
Sea freight is economical for high-volume wholesale orders. Air freight is available for urgent programs, while express courier is suitable for qualification samples and pilot quantities. DDP service can be evaluated for selected markets.
Frequently Asked Questions
Q1. What type of stopper is shown in the image?
It appears to be a flanged pharmaceutical rubber vial stopper with a hollow plug structure. Exact application must be confirmed using dimensions and technical specifications.
Q2. Can this stopper be used for penicillin bottles?
It can be matched to compatible penicillin vial formats. The vial neck, stopper dimensions, and aluminum closure must be verified as one system.
Q3. Is red the only available color?
No. Elastomer color depends on formulation and project specification. Alternative options can be evaluated.
Q4. Do you provide bromobutyl and chlorobutyl stoppers?
Yes. The appropriate material depends on the intended formulation, process, and qualification requirements.
Q5. Can you supply matching aluminum caps?
Yes. Aluminum crimp seals and colored flip-off caps are available for compatible vial systems.
Q6. Can you supply the pharmaceutical glass vial too?
Yes. Clear and amber glass vials can be coordinated with the stopper and closure.
Q7. Are these stoppers sterile?
Sterility depends on the specific supply configuration. Sterile, ready-to-sterilize, washed, or other conditions must be defined in the purchase specification.
Q8. What information is required for matching?
Send your vial neck specification, current stopper dimensions or sample, cap size, application, expected annual quantity, and destination market.
Buyer Feedback
★★★★★ Better fit across our vial lots
“Matching the stopper against our actual vial dimensions reduced seating variation and simplified our production trials.”
— Packaging Engineer, Healthcare Manufacturer
★★★★★ Complete closure sourcing reduced vendor coordination
“We ordered the vial, rubber stopper, and aluminum-plastic cap as one project, which made technical communication much easier.”
— Procurement Manager, Diagnostic Products Company
★★★★★ Stable dimensions for repeat orders
“The stopper flange and plug dimensions remained consistent with our approved specification across repeat shipments.”
— Operations Lead, Contract Packaging Facility
Related Product Categories
- Pharmaceutical Rubber Stoppers
- Injection Vial Stoppers
- Bromobutyl Rubber Stoppers
- Chlorobutyl Rubber Stoppers
- Lyophilization Stoppers
- Pharmaceutical Glass Vials
- Penicillin Bottles
- Aluminum Flip-Off Caps
- Aluminum Crimp Seals
- Pharmaceutical Containers
- Bottle Packaging
- Supplement Packaging
- Jar Packaging
- Flexible Packaging
- Pharmaceutical Folding Cartons
- Custom Packaging Services
Visit our products page for complete packaging development support.
Request a Stopper Match for Your Pharmaceutical Vial
Send your vial neck size or drawing, current stopper sample if available, intended application, required elastomer type, aluminum cap specification, estimated quantity, and destination market. A physical vial and closure sample can significantly shorten compatibility evaluation when exact dimensions are unknown.
Supply-Packagings provides OEM, ODM, factory-direct manufacturing and wholesale custom packaging support across pharmaceutical rubber stoppers, glass vials, bottle systems, aluminum caps, jars, pouches, trays, and secondary cartons.
For specification matching, samples, MOQ, production lead time, documentation requirements, and international logistics, Contact Us.
评价
目前还没有评价